Join
today

Boliven PRO is more than just patent search

  • Build and save lists using the powerful Lists feature
  • Analyze and download your search results
  • Share patent search results with your clients

Patents »

US20050214803: High-density amine-functionalized surface

Share

Filing Information

Inventor(s) Guo Wang ·
Assignee(s) SRU BIOSYSTEMS, LLC ·
Correspondent MCDONNELL BOEHNEN HULBERT & BERGHOFF LLP ·
Application Number US10983511
Filing date 11/08/2004
Publication date 09/29/2005
Predicted expiration date 11/08/2024
U.S. Classifications 435/6  · 427/2.11  · 435/7.5  · 435/287.1  ·
International Classifications --
Kind CodeA1
43 Claims, 8 Drawings


Abstract

A method for providing amine functional groups on a surface for binding proteins, peptides, DNAs, cells, small molecules, and other chemical or biological molecules that are of interests in the areas of proteomic, genomic, pharmaceutical, drug discovery, and diagnostic studies.

Independent Claims | See all claims (43)

  1. 1. A method for preparing a high-density amine-functionalized surface, comprising: (a) treating a surface with epoxy silane to form an epoxy-functional surface; and (b) attaching one or more amine-containing polymers to the epoxy-functional surface by adding a solution comprising one or more amine-containing polymers to the epoxy-functional surface under conditions where one or more amine-containing polymers react with the epoxy-functional surface; whereby a high-density amine-functionalized surface is formed.
  2. 3. A biosensor comprising the high-density amine-functionalized surface.
  3. 27. A high-density amine-functionalized polymeric matrix, comprising one or more amine-containing polymers covalently attached to a surface through a functional epoxy, wherein the amine-containing polymers are the same or different, and wherein the amine-containing polymers comprise two or more amine groups.
  4. 35. A biosensor comprising a high-density amine-functionalized surface, wherein the high-density amine-functionalized surface is prepared by the method comprising: (a) treating a surface with epoxy silane to form an epoxy-functional surface; and (b) attaching one or more amine-containing polymers to the epoxy-functional surface by adding a solution comprising one or more amine-containing polymers to the epoxy-functional surface under conditions where one or more amine-containing polymers react with the epoxy-functional surface; whereby a high-density amine-functionalized surface is formed.

References Cited

The current document has no citations.

Patent Family

The current document is not in a family.