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US20090136528: NOVEL IMMUNOGENIC EPITOPE FOR IMMUNOTHERAPY

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Filing Information

Inventor(s) Harpreet SINGH · Steffen WALTER · Toni WEINSCHENK · Norbert HILF · Oliver Schoor · Claudia Lemmel ·
Assignee(s) Immatics Biotechnologies GmhH ·
Correspondent Baker Donelson Bearman, Caldwell & Berkowitz, PC ·
Application Number US12180045
Filing date 07/25/2008
Publication date 05/28/2009
Predicted expiration date 07/25/2028
U.S. Classifications 424/185.1  · 435/320.1  · 530/326  · 530/325  · 530/324  · 530/403  · 536/235  · 530/327  · 435/325  · 435/691  · 435/377  · 435/372.3  · 424/937.1  · 530/328  ·
International Classifications A61K3512  · A61K3900  · A61P3500  · C07H2100  · C07K14435  · C07K706  · C07K708  · C12N1563  · C12N500  · C12N508  · C12P2100  ·
Kind CodeA1
Foreign Priority EP07014797.0 - 07/27/2007 ·
21 Claims, 24 Drawings


Abstract

The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumour-associated T-helper cell peptide epitopes, alone or in combination with other tumour-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions which stimulate anti-tumour immune responses. The present invention relates to novel peptide sequences and their variants derived from HLA class I and class II molecules of human tumour cells which can be used in vaccine compositions for eliciting anti-tumour immune responses.

Independent Claims | See all claims (21)

  1. 1. A peptide comprising a sequence that is selected from the group of SEQ ID NO: 1 to SEQ ID NO: 29 or a variant thereof which is 80% homologous to SEQ ID NO: 1 to SEQ ID NO: 29 or a variant, which will induce T cells cross-reacting with said peptide.

References Cited

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Referenced By

Document NumberAssigneeInventorsIssue/Pub Date
US8017591 Molgen AG Bernadette Brzezicha et al. Sep 2011

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