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US4160008: Multilayered test device for determining the presence of a liquid sample component, and method of use

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Filing Information

Inventor(s) Leonard P. Fenocketti · Myron C. Rapkin ·
Assignee(s) Miles Laboratories, Inc. ·
Attorney/Agent(s) Gorman, Jr.; Edward H. ·
Primary Examiner Joseph Scovronek ·
Assistant Examiner Michael S. Marcus ·
Application Number US5872560
Filing date 01/26/1978
Issue date 07/03/1979
Predicted expiration date 01/26/1998
U.S. Classifications 422/401  · 435/4  · 435/14  · 422/421  · 435/805  · 436/165  · 436/86  ·
International Classifications G01N 3122  ·
Kind CodeA
International Classifications 23253 TP;230 B ·
16 Claims, No Drawings


Abstract

A test device for determining the presence of a liquid sample constituent. The device comprises a base support member having attached to it an indicator member which produces a detectable response, such as a color change, in the presence of the sample constituent. The indicator member comprises an upper reagent layer, a lower absorbent layer and a substantially sample-impervious barrier layer between the upper and lower layers. The indicator member is attached to the base member along the lower side of the absorbent layer.

Independent Claims | See all claims (16)

  1. 1. Test means for determining the presence of a constituent in a liquid sample, said test means comprising a layer of absorbent material having fixedly laminated to each of the opposite faces thereof respectively, a substantially liquid impervious layer, and a reagent layer overlaying at least one of said liquid impervious layers.
  2. 6. A test device for determining the presence of a constituent in a liquid sample comprising a common substantially liquid impervious support member having a flat surface, first and second layers of absorbent material fixedly laminated to said surface in spaced relation, each of said absorbent layers having a substantially liquid impervious layer fixedly laminated to the surface thereof opposite said support member, and a reagent layer overlaying each of said liquid impervious layers.
  3. 8. A test device for determining the presence of a constituent in a liquid sample, the device comprising (a) a base support member having affixed thereto (b) an indicator member, the indicator member comprising an upper reagent layer, a lower absorbent layer and a substantially sample-impervious barrier layer separating said upper and lower layers, said upper and lower layers being fixedly laminated to said barrier layer.
  4. 12. A test device for determining the presence of a constituent in a liquid sample, said device comprising (a) a base support member having a top side, and (b) an indicator member having a bottom side affixed to said top side of the base support member, said indicator member comprising an upper reagent layer and a lower absorbent layer, both of said layers being fixedly laminated to a substantially sample-impervious barrier layer separating said upper and lower layers.

References Cited

U.S. Patent Documents

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US3907503 MILES LAB Betts Sep 1975
US3993451 Miles Laboratories, Inc. Verbeck Nov 1976
US4061468 Boehringer Mannheim GmbH Lange et al. Dec 1977
US4076502 Miles Laboratories, Inc. Dugle et al. Feb 1978

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