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US4283289: Blood filter for leukocytes

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Filing Information

Inventor(s) Richard P. Meyst · Ronald M. Porten ·
Assignee(s) Baxter Travenol Laboratories, Inc. ·
Attorney/Agent(s) Paul C. Flattery ·
Primary Examiner Spear, Jr.; Frank A. ·
Application Number US6068829
Filing date 08/22/1979
Issue date 08/11/1981
Predicted expiration date 08/22/1999
U.S. Classifications 210/448  · 210/450  ·
International Classifications B01D 2706  ·
Kind CodeA
International Classifications 210456;450;448;DIG. 23;23 R;505;927 ·
12 Claims, No Drawings


Abstract

A leukocyte filter for blood which includes a housing defining a blood inlet and outlet at respective ends thereof, with the housing enclosing and carrying a tubular, non-woven fiber filter element, with one of the inlet and outlet communicating with the interior of the tubular filter element, and the other of the inlet and outlet communicating with the exterior of the tubular filter element. In the tubular filter element, essentially all of the fibers define diameters of 10 to 100 microns, and have other diameter restrictions described herein, with the fibers being bonded together to define a generally fixed, average interstitial spacing which is less at the inner surface of the tubular filter element than at the outer surface thereof. The air permeability of the filter per square foot is preferably from essentially 15 to 45 SCFM at one half inch of water.

Independent Claims | See all claims (12)

  1. 1. In a leukocyte filter for blood a housing defining a blood inlet and an outlet at respective ends thereof, said housing enclosing and carrying a tubular, non-woven fiber filter element with one of said inlet and outlet communicating with the interior of said tubular filter element, and the other of said inlet and outlet communicating with the exterior of said tubular filter element, the improvement comprising, in combination:said tubular fiber filter element constituting a depth filter having a thickness of 0.2 to 0.6 inch, essentially all of said fibers defining diameters of 10 to 100 microns, from 10 to 70 percent by weight of said fiber defining fiber diameters of from 10 to 20 microns, and at least 50 percent by weight of said fibers having diameters of no more than 35 microns, said fibers being bonded together to define a generally fixed average interstitial spacing which is less at the inner surface of said tubular filter element than at the outer surface thereof, the air permeability of one square foot of said filter being from essentially 15 to 45 SCFM at 1/2 inch of water.
  2. 7. In a white cell filter for blood a housing defining a blood inlet and an outlet at respective ends thereof, said housing enclosing and carrying a tubular, non-woven fiber filter element with one of said inlet and outlet communicating with the interior of said tubular filter element and the other of said inlet and outlet communicating with the exterior thereof, said filter element defining fiber diameters adapted to adsorb and temporarily hold white cells from blood passing therethrough, the improvement comprising, in combination:said fiber filter element having a thickness of 0.2 to 0.6 inch, said fibers being bonded together to define a generally fixed average interstitial spacing which is gradated in size to be less at the inner surface of said tubular filter element than at the outer surface thereof, and in which said filter element is retained in said housing at both ends by first and second blood-compatible, elastomeric retention members, the ends of said filter element being integrally attached to and commingled with said retention members, said first retention member also defining a housing end seal and further defining an aperture for one of said inlet and outlet, said second retention member defining a seal of a bore of said tubular filter element and defining about its periphery a plurality of spaced, peripheral ribs engaging the inner wall of said housing and defining flow channels between said ribs, said ribs being compressed by said inner wall to insure the seal between the seal of said filter element and the second retention member.

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Patent Family

Document NumberAssigneeInventorsIssue/Pub Date
DE3028988 BAXTER TRAVENOL LAB MEYST RICHARD P et al. Mar 1981
GB2056301 BAXTER TRAVENOL LAB Mar 1981
US4283289 Baxter Travenol Laboratories, Inc. Richard P. Meyst et al. Aug 1981