Join
today

Boliven PRO is more than just patent search

  • Build and save lists using the powerful Lists feature
  • Analyze and download your search results
  • Share patent search results with your clients

Patents »

US4797368: Adeno-associated virus as eukaryotic expression vector

Share

Filing Information

Inventor(s) Barrie J. Carter · Jon D. Tratschin ·
Assignee(s) The United States of America as represented by the Department of Health and Human Services ·
Attorney/Agent(s) Holman & Stern ·
Primary Examiner Thomas G. Wiseman ·
Assistant Examiner Stephanie Seidman ·
Application Number US6712236
Filing date 03/15/1985
Issue date 01/10/1989
Predicted expiration date 01/10/2006
U.S. Classifications 435/320  · 435/68  ·
International Classifications C12N 700  ·
Kind CodeA
International Classifications 435172.3;240;317;68;235;91;70;320;235 ·
4 Claims, No Drawings


Abstract

The present invention relates to a vector comprising part of AAV DNA contained in a plasmid and capable of being packaged into AAV particles and functioning as a vector for stable integration and expression of a gene in eukaryotic cells when under control of an AAV transcription promoter. A method of preparing such plasmids which are packagable and rescuable is also described.

Independent Claims | See all claims (4)

  1. 1. A vector comprising part of AAV DNA contained in a plasmid and capable of being packaged into AAV particles and functioning as a vector for stable maintenance or expression of a gene or a DNA sequence in eukaryotic cells when under control of an AAV transcription promotor.

References Cited

U.S. Patent Documents

Document NumberAssigneesInventorsIssue/Pub Date
US4419446 The United States of America as represented by the Department of Health and Human Services Howley et al. Dec 1983

Other Publications

Tratschin, J. et al. (Sep. 1984) J. Virol 51:611-619.
Tratschin, J. et al. (Oct. 1984) Molec. Cell. Biol. 4:2072-2081.
Hermonat, P. and N. Muzyczka (Oct. 1984) PNAS 81:6466-6470.
Laughlin et al., Gene, 23 (1983) 65-73.

Referenced By

Document NumberAssigneeInventorsIssue/Pub Date
FR2678948 AGRONOMIQUE INST NAT RECH MAX BERGOIN et al. Jan 1993
US8278428 John Guy John Guy et al. Oct 2012
US8636998 --
EP1164195 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Barrier J. Carter et al. Oct 2010
EP1681354 Aventis Pharma S.A. Alexis Bemelmans et al. Jul 2006
EP1757617 Biogen Idec MA Inc. Michele Sanicola-Nadel et al. Feb 2007
EP1935979 Novartis Vaccines and Diagnostics S.r.l. Vega Masignani et al. Sep 2008
EP0488528 APPLIED IMMUNE SCIENCES, INC. Jane Lebkowski et al. Nov 1995
EP0644944 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES Barrie J. CARTER et al. Nov 2001
EP0836484 THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK Xiaohuai ZHOU et al. Aug 2006
US5474935 The United States of America as represented by the Department of Health and Human Services Saswati Chatterjee et al. Dec 1995
US5478745 University of Pittsburgh Richard J. Samulski et al. Dec 1995
US6127525 Cornell Research Foundation, Inc. Ronald G. Crystal et al. Oct 2000
US6261551 The Trustees of the University of Pennsylvania James M. Wilson et al. Jul 2001
US5658785 Children's Hospital, Inc. Philip R. Johnson Aug 1997
US5658776 Targeted Genetics Corporation Terence R. Flotte et al. Aug 1997
US5773289 University of Pittsburgh Richard Jude Samulski et al. Jun 1998
US5858775 Children's Hospital, Inc. Philip R. Johnson Jan 1999
US5866696 The United States of America as represented by the Department of Health and Human Services Barrie J. Carter et al. Feb 1999
US6284492 Large Scale Biology Corporation Jon Donson et al. Sep 2001
US5057417 Genentech, Inc. Hammonds; R. Glenn et al. Oct 1991
US5173414 Applied Immune Sciences, Inc. Jane S. Lebkowski et al. Dec 1992
US5688676 Research Foundation of State University of New York Xiaohuai Zhou et al. Nov 1997
US5863541 University of Pittsburgh Richard Jude Samulski et al. Jan 1999
US6110456 Yale University Mathew John During Aug 2000
US5646034 Michael Mamounas et al. Jul 1997
US5693531 The United States of America as represented by the Department of Health and Human Services John A. Chiorini et al. Dec 1997
US5719057 Merck Sharpe & Dohme Ltd. Karen Louise Hadingham et al. Feb 1998
US5869305 The University of Pittsburgh Richard Jude Samulski et al. Feb 1999
US5866785 Biosource Technologies, Inc. Jon Donson et al. Feb 1999
US5786211 Children's Hospital, Inc. Philip R. Johnson Jul 1998
US6165754 Cornell Research Foundation, Inc. Ronald G. Crystal et al. Dec 2000
US6225456 University Technololy Corporation Trent Gu et al. May 2001
US5693522 Chiron Viagene, Inc. Sunil Chada et al. Dec 1997
US5691176 Applied Immune Sciences, Inc. Jane S. Lebkowski et al. Nov 1997
US5919676 AdVec, Inc. Frank L. Graham et al. Jul 1999
US5851521 Case Western Reserve University Didier Branellec et al. Dec 1998
US6040183 University of North Carloina at Chapel Hill Forrest K. Ferrari et al. Mar 2000
US5990279 The United States of America as represented by the Department of Health and Human Services Barrie J. Carter et al. Nov 1999
US6063627 GenVec, Inc. Duncan L. McVey et al. May 2000
US6329190 GenVec, Inc. Thomas J. Wickham et al. Dec 2001
US5354678 Applied Immune Sciences, Inc. Jane S. Lebkowski et al. Oct 1994
US5589377 Rhone-Poulenc Rorer Pharmaceuticals, Inc. Jane S. Lebkowski et al. Dec 1996
US5436146 The Trustees of Princeton University Thomas E. Shenk et al. Jul 1995
US6054566 Biosource Technologies, Inc. Jon Donson et al. Apr 2000
US5677158 Research Foundation of State University of New York Xiaohuai Zhou et al. Oct 1997
US5780280 Rhone-Poulenc Rorer Pharmaceuticals, Inc. Jane S. Lebkowski et al. Jul 1998
US6120764 AdVec, Inc. Frank L. Graham et al. Sep 2000
US6086913 University of British Columbia Patrick Tam et al. Jul 2000
US6153435 Cornell Research Foundation, Inc. Ronald G. Crystal et al. Nov 2000
US6251677 The Trustees of the University of Pennsylvania James M. Wilson et al. Jun 2001
US5741683 The Research Foundation of State University of New York Xiaohuai Zhou et al. Apr 1998
US5801030 GenVec, Inc. Duncan L. McVey et al. Sep 1998
US5989540 The United States of America as represented by the Department of Health & Human Services Barrie J. Carter et al. Nov 1999
US5770442 Cornell Research Foundation, Inc. Thomas J. Wickham et al. Jun 1998
US5139941 University of Florida Research Foundation, Inc. Nicholas Muzyczka et al. Aug 1992
US5587308 The United States of America as represented by the Department of Health & Human Services Barrie J. Carter et al. Dec 1996
US5681731 Applied Immune Sciences, Inc. Jane S. Lebkowski et al. Oct 1997
US5869040 Biogen, Inc Xiao-Oiang Oin Feb 1999
US6027931 Avigen, Inc. George Natsoulis et al. Feb 2000
US6093570 The University of North Carolina at Chapel Hill Forrest K. Ferrari et al. Jul 2000
US6270996 The Trustees of the University of Pennsylvania James M. Wilson et al. Aug 2001
US5585254 University of Colorado Foundation, Inc. Ian H. Maxwell et al. Dec 1996
US5688763 Hammonds, Jr.; R. Glenn et al. Nov 1997
US6080569 Merck & Co., Inc. Frank L. Graham et al. Jun 2000
US6204059 University of Pittsburgh Richard Jude Samulski et al. Mar 2001
US5688675 Research Foundation of State University of New York Xiaohuai Zhou et al. Nov 1997
US5753500 The Trustees of Princeton University Thomas E. Shenk et al. May 1998
US5837484 Medical College of Ohio James P. Trempe et al. Nov 1998
US5889190 Biosource Technologies, Inc. Jon Donson et al. Mar 1999
US6187757 ARIAD Pharmaceuticals, Inc. Timothy P. Clackson et al. Feb 2001
US6165781 The United States of America as represented by the Department of Health and Human Services Barrie J. Carter et al. Dec 2000
US6057155 GenVec, Inc. Thomas J. Wickham et al. May 2000
US6180613 The Rockefeller University Michael G. Kaplitt et al. Jan 2001
US6140087 AdVec, Inc. Frank L. Graham et al. Oct 2000
US5871982 The Trustees of the University of Pennsylvania James M. Wilson et al. Feb 1999
US5756283 The Trustees of the University of Pennsylvania James M. Wilson et al. May 1998
US6057152 University of Pittsburgh Richard Jude Samulski et al. May 2000
US6365403 Avigen, Inc. Georges Natsoulis et al. Apr 2002
US6913922 Crucell Holland B.V. Abraham Bout et al. Jul 2005
US7192740 Large Scale Biology Corporation Jonathan Donson et al. Mar 2007
US7229823 SAMULSKI RICHARD JUDE Richard Jude Samulski et al. Jun 2007
US7358085 Sangamo Biosciences, Inc. H. Steve Zhang et al. Apr 2008
US7563459 The United States of America as represented by the Department of Vetrans Affairs Catherine A. Phillips Jul 2009
US6387368 The Trustees of the University of Pennsylvania James M. Wilson et al. May 2002
US6649595 ARIAD Gene Therapeutics, Inc. Timothy P. Clackson et al. Nov 2003
US6929946 Crucell Holland B.V. Ronald Vogels et al. Aug 2005
US7235233 Crucell Holland B.V. Menzo Jans Emco Havenga et al. Jun 2007
US7560538 University of Pittsburgh Chihiro Koike Jul 2009
US6458587 The University of North Carolina at Chapel Hill Forrest K. Ferrari et al. Oct 2002
US6951753 The 501 Trustees of Princeton University Thomas E. Shenk et al. Oct 2005
US7179645 Antigen Express, Inc. Robert E. Humphreys et al. Feb 2007
US7414026 Vlaams Interuniversitair Instituut voor Biotechnologie VZW Rudi Beyaert et al. Aug 2008
US7510875 Introgen Therapuetics, Inc. Shuyuan Zhang et al. Mar 2009
US6512161 Aventis Pharmaceuticals, Inc. Didier Rouy et al. Jan 2003
US6503888 The Rockefeller University Michael G. Kaplitt et al. Jan 2003
US6566118 Targeted Genetics Corporation Edward M. Atkinson et al. May 2003
US6656471 Board of Regents, The University of Texas System K. Jagannadha Sastry et al. Dec 2003
US6589523 Teruhiko Toyo-Oka Jul 2003
US7045347 Advec, Inc. Frank L. Graham et al. May 2006

Patent Family

The current document is not in a family.