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US5135719: Blood separation device comprising a filter and a capillary flow pathway exiting the filter

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Filing Information

Inventor(s) Robert S. Hillman · Ian Gibbons ·
Assignee(s) Biotrack, Inc. ·
Attorney/Agent(s) Cooley Godward Castro Huddleson & Tatum ·
Primary Examiner Hill, Jr.; Robert J. ·
Assistant Examiner David Redding ·
Application Number US7607618
Filing date 10/23/1990
Issue date 08/04/1992
Predicted expiration date 08/04/2009
U.S. Classifications 422/101  · 422/58  ·
International Classifications G01N 118  ·
Kind CodeA
International Classifications 42258;66;101 ·
Related U.S. Application DataThis application is a continuation of U.S. application Ser. No. 07/163,392, filed Mar. 2, 1988, now abandoned, which is a division of U.S. application Ser. No. 924,633, filed Oct. 29, 1986, now U.S. Pat. No. 4,753,776.
7 Claims, No Drawings


Abstract

A method for separating plasma from red blood cells and a device utilizing the method in which a low-pressure filter is interposed in a pathway between an inlet port and a reaction area. The sole driving force for the movement of plasma from the filter to the reaction area is capillary force provided by a tubular capillary. The filter is selected from glass microfiber filters of specified characteristics, which can operate in the absence of agglutinins, and filters capable of separating agglutinated red cells from plasma, which require the use of an agglutinin.

Independent Claims | See all claims (7)

  1. 1. In a clinical diagnostic device comprising a housing having a fluid inlet port, a vented reaction area, and a unitary capillary pathway connecting said inlet port and said reaction area, said housing constructed such that said pathway conducts liquid exclusively as a result of capillary pressure originating in said pathway, the improvement which comprises:a low-pressure filter in said inlet port and directly adjacent to said capillary pathway, wherein said filter is constructed so as to separate agglutinated red blood cells from plasma, wherein said filter further contains a soluble agglutinin for agglutinating red blood cells selected from the group consisting of antibodies and lectins, wherein whole blood applied to said inlet port contacts said soluble agglutinin concurrently with contacting said filter and plasma is separated from whole blood which flows into said capillary pathway in the absence of externally applied pressure.

References Cited

U.S. Patent Documents

Document NumberAssigneesInventorsIssue/Pub Date
US3843324 RESEARCH CORP Edelman et al. Oct 1974
US4327073 Huang Apr 1982
US4426451 Eastman Kodak Company Columbus Jan 1984
US4623461 Murex Corporation Hossom et al. Nov 1986
US4692411 GHOSE RABINDRA N Ghose Sep 1987
US4753776 Biotrack, Inc. Hillman et al. Jun 1988
US4808533 Shanksville Corporation NV Fabricius et al. Feb 1989
US4816224 Boehringer Mannheim GmbH Vogel et al. Mar 1989
US4843017 Dickinson and Company Becton Oberhardt et al. Jun 1989
US4933092 Abbott Laboratories Aunet et al. Jan 1990

Referenced By

Document NumberAssigneeInventorsIssue/Pub Date
EP1120650 Roche Diagnostics GmbH Raghbir Singh Bhullar et al. Aug 2001
AU689614 NIHON MEDIPHYSICS CO LTD TAGUCHI TAKAYUKI et al. Apr 1998
AU754779 PURDUM HOWARD E PURDUM HOWARD E Nov 2002
EP1125591 Eisuke Maehata Hiromi Nanba et al. Aug 2001
EP1236514 Biosite Incorporated Kenneth Francis Buechler et al. Nov 2009
EP1096254 Roche Diagnostics Corporation Raghbir S. Bhullar et al. Apr 2005
EP1531003 STEAG microParts GmbH Blankenstein, Gert, Dr. et al. May 2005
EP1315553 peS Gesellschaft fr medizinische Diagnose-Systeme mbH Peter RAUCH et al. Dec 2006
EP0920356 BIOSITE DIAGNOSTICS INC. BUECHLER, Kenneth, Francis et al. Dec 2002
US5700695 Zia Yassinzadeh Zia Yassinzadeh et al. Dec 1997
US5922604 Gene Tec Corporation Marilyn Stapleton et al. Jul 1999
US6245244 Micro Diagnostic Innovations Nederland B.V. Felix Wilhelmus Marie De Rooij Jun 2001
US5660798 ActiMed Laboratories, Inc. Sonal R. Doshi et al. Aug 1997
US6036659 FlexSite Diagnostics, Inc. Robert A. Ray et al. Mar 2000
US6258045 FlexSite Diagnostics, Inc. Robert A. Ray et al. Jul 2001
US5589399 First Medical, Inc. Michael P. Allen et al. Dec 1996
US6069014 Beckman Coulter, Inc. Wayne H. Schrier et al. May 2000
US6106732 Binax Services, Inc. James Bennett Johnston et al. Aug 2000
US5681529 Nihon Medi-Physics Co., Ltd. Takayuki Taguchi et al. Oct 1997
US5478751 Abbott Laboratories Gary M. Oosta et al. Dec 1995
US5550060 Chronomed, Inc. Alexander Saunders et al. Aug 1996
US5879951 SmithKline Diagnostics, inc. Vincent A. Sy Mar 1999
US6241886 Toyo Boseki Kabushiki Kaisha Tomohiro Kitagawa et al. Jun 2001
US5364533 Sanwa Kagaku Kenkyusho Co., Ltd. Shinji Ogura et al. Nov 1994
US5766552 ActiMed Laboratories, Inc. Sonal R. Doshi et al. Jun 1998
US6008059 Beckman Coulter, Inc. Wayne H. Schrier et al. Dec 1999
US6177283 FlexSite Diagnostics, Inc. Robert A. Ray Jan 2001
US6319719 Roche Diagnostics Corporation Raghbir S. Bhullar et al. Nov 2001
US5460974 Miles Inc. Mary B. Kozak et al. Oct 1995
US5665238 The United States of America as represented by the Administrator of the National Aeronautics and Space Administration Peggy A. Whitson et al. Sep 1997
US5441894 Abbott Laboratories Carole L. Coleman et al. Aug 1995
US5652148 Actimed Laboratories, Inc. Sonal R. Doshi et al. Jul 1997
US5939252 Donald J. Lennon et al. Aug 1999
US5981294 Metrika, Inc. Joel M. Blatt et al. Nov 1999
US6197598 Beckman Coulter, Inc. Wayne H. Schrier et al. Mar 2001
US6039868 First Medical, Inc. Michael P. Allen et al. Mar 2000
US5798272 First Medical, Inc. Michael P. Allen et al. Aug 1998
US7043821 LifeScan, Inc. Alastair McIndoe Hodges May 2006
US7588730 Biosite, Inc. Kenneth F. Buechler et al. Sep 2009
US6939312 LifeScan, Inc. Alastair Hodges et al. Sep 2005
US6808638 Throwleigh Technologies, L.L.C. Howard E. Purdum Oct 2004
US6663833 Strategic Diagnostics Inc. James W. Stave et al. Dec 2003
US7150995 Metrika, Inc. Zongcen Charles Xie et al. Dec 2006
US6406672 Roche Diagnostics Raghbir Singh Bhullar et al. Jun 2002
US6612111 Lifescan, Inc. Alastair Hodges et al. Sep 2003
US6936473 Leisure, Inc. Hiromi Nanba et al. Aug 2005
US6571651 LifeScan, Inc. Alastair McIndoe Hodges Jun 2003
US6696240 Micronix, Inc. Hans G. Kloepfer et al. Feb 2004
US6355174 Phoenix Medical Limited Patricia Mary Beckett Robertson Mar 2002
US6823750 LifeScan, Inc. Alastair McIndoe Hodges Nov 2004
US7131342 Lifescan, Inc. Alastair McIndoe Hodges Nov 2006
US6403384 Umedik, Inc. Peter Lea Jun 2002
US7871781 Phadia AB Gerd Rundstrm et al. Jan 2011
US7872734 Optiscan Biomedical Corporation James R. Braig et al. Jan 2011
US7875047 Pelikan Technologies, Inc. Dominique Freeman et al. Jan 2011
US7909774 Pelikan Technologies, Inc. Dominique Freeman et al. Mar 2011
US7909775 Pelikan Technologies, Inc. Don Alden et al. Mar 2011
US7909777 Pelikan Technologies, Inc Dominique M. Freeman et al. Mar 2011
US7909778 PeliKan Technologies, Inc. Dominique Freeman et al. Mar 2011
US7901365 Pelikan Technologies, Inc. Dominique Freeman et al. Mar 2011
US7892183 Pelikan Technologies, Inc. Dirk Boecker et al. Feb 2011
US7914465 Pelikan Technologies, Inc. Dominique M. Freeman et al. Mar 2011
US7938787 Pelikan Technologies, Inc. Dominique M. Freeman et al. May 2011
US7959582 Pelikan Technologies, Inc. Dominique Freeman et al. Jun 2011
US7976476 Pelikan Technologies, Inc. Dom Freeman et al. Jul 2011
US7988644 Pelikan Technologies, Inc. Dominique Freeman et al. Aug 2011
US7988645 Pelikan Technologies, Inc. Dominique Freeman et al. Aug 2011
US7981055 Pelikan Technologies, Inc. Dominique Freeman et al. Jul 2011
US7981056 Pelikan Technologies, Inc. Barry Briggs et al. Jul 2011
US8007446 Pelikan Technologies, Inc. Dirk Boecker et al. Aug 2011
US7999927 Optiscan Biomedical Corporation James R. Braig et al. Aug 2011
US8016774 Pelikan Technologies, Inc. Dominique Freeman et al. Sep 2011
US8062231 Pelikan Technologies, Inc. Dirk Boecker et al. Nov 2011
US8097171 Akers Biosciences, Inc. David Milunic et al. Jan 2012
US8079960 Pelikan Technologies, Inc. Barry Dean Briggs et al. Dec 2011
US8123700 Pelikan Technologies, Inc. Don Alden et al. Feb 2012
US8235915 Sanofi-Aventis Deutschland GmbH Dominique Freeman et al. Aug 2012
US8251921 Sanofi-Aventis Deutschland GmbH Barry Dean Briggs et al. Aug 2012
US8221334 Sanofi-Aventis Deutschland GmbH Dominique Freeman et al. Jul 2012
US8216154 Sanofi-Aventis Deutschland GmbH Dominique Freeman et al. Jul 2012
US8211037 Pelikan Technologies, Inc. Dominique Freeman et al. Jul 2012
US8162853 Pelikan Technologies, Inc. Dominique Freeman et al. Apr 2012
US8202231 Sanofi-Aventis Deutschland GmbH Dominique M. Freeman et al. Jun 2012
US8206319 Sanofi-Aventis Deutschland GmbH Dominique Freeman et al. Jun 2012
US8206317 Sanofi-Aventis Deutschland GmbH Dominique Freeman et al. Jun 2012
US8197421 Pelikan Technologies, Inc. Dominique M. Freeman et al. Jun 2012
US8197423 Pelikan Technologies, Inc. Dominique Freeman et al. Jun 2012
US8157748 Pelikan Technologies, Inc. Barry Dean Briggs et al. Apr 2012
US8262614 Pelikan Technologies, Inc. Dominique Freeman et al. Sep 2012
US8282577 Sanofi-Aventis Deutschland GmbH Don Alden et al. Oct 2012
US8282576 Sanofi-Aventis Deutschland GmbH Travis Marsot et al. Oct 2012
US8333710 Sanofi-Aventis Deutschland GmbH Dominique M. Freeman et al. Dec 2012
US8267870 Sanofi-Aventis Deutschland GmbH Dominique M. Freeman et al. Sep 2012
US8296918 Sanofi-Aventis Deutschland GmbH Don Alden et al. Oct 2012
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