Join
today

Boliven PRO is more than just patent search

  • Build and save lists using the powerful Lists feature
  • Analyze and download your search results
  • Share patent search results with your clients

Patents »

US5645084: Method for spinal fusion without decortication

Share

Filing Information

Inventor(s) William F. McKay ·
Assignee(s) Danek Medical, Inc. ·
Attorney/Agent(s) Woodard, Enhardt, Naughton Moriarty & McNett ·
Primary Examiner Michael Buiz ·
Assistant Examiner Mark S. Leonardo ·
Application Number US8482038
Filing date 06/07/1995
Issue date 07/08/1997
Predicted expiration date 06/07/2015
U.S. Classifications 128/898  · 435/691  ·
International Classifications A61B 1900  ·
Kind CodeA
International Classifications 60660;61;72;76 ·
28 Claims, No Drawings


Abstract

Surgical procedures for stabilizing a spine include exposing a portion of each of adjacent vertebrae requiring fusion and placing an osteoinductive material within an area between the portions of the adjacent vertebrae in contact with the cortical bone of the portions. In another aspect, surgical procedures for stabilizing a spine are provided which include exposing a portion of each of adjacent vertebrae requiring fusion, adding an osteoinductive cytokine to a carrier material and placing the carrier material between the portions of the adjacent vertebrae in contact with the cortical bone of the portions.

Independent Claims | See all claims (28)

  1. 1. A surgical procedure for stabilizing, vertebrae in a spine, comprising the steps of:exposing cortical bone of a portion of each of adjacent vertebrae each said portion being outside an intervertebral disc space between the adjacent vertebrae; andplacing an osteoinductive material within an area between the portions of the adjacent vertebrae in contact with only the cortical bone of the portions.
  2. 22. A surgical procedure for stabilizing a spine, comprising the steps of:exposing cortical bone of a portion of each of adjacent vertebrae in the spine; andinjecting an osteoinductive material into the disc space between the adjacent vertebrae and in contact with only the cortical bone of the portions.
  3. 23. A surgical procedure for stabilizing a spine, comprising the steps of:exposing cortical bone of a portion of each of adjacent vertebrae each said portion being outside an intervertebral disc space between the adjacent vertebrae;adding an osteoinductive cytokine to a carrier material; andplacing the carrier material between said portions of the adjacent vertebrae in contact with only the nondecorticated bone of the portions.

References Cited

U.S. Patent Documents

Document NumberAssigneesInventorsIssue/Pub Date
US4294753 The Regents of the University of California Urist Oct 1981
US4526909 Regents of the University of California Urist Jul 1985
US4619989 The Regents of the University of Cal. Urist Oct 1986
US4761471 The Regents of the University of California Urist Aug 1988
US4789732 Regents of the University of California Urist Dec 1988
US4857456 The Regents of the University of California Urist Aug 1989
US4877864 Genetics Institute, Inc. Wang et al. Oct 1989
US5013649 Genetics Institute, Inc. Wang et al. May 1991
US5106748 Genetics Institute, Inc. Wozney et al. Apr 1992
US5108922 Genetics Institute, Inc. Wang et al. Apr 1992
US5116738 Genetics Institute, Inc. Wang et al. May 1992
US5141905 ROSEN VICKI A Rosen et al. Aug 1992
US5168050 Genentech, Inc. Hammonds, Jr. et al. Dec 1992
US5187076 Genetics Institute, Inc. Wozney et al. Feb 1993
US5208219 Celtrix Pharmaceuticals Inc. Ogawa et al. May 1993
US5318898 Genetics Institute, Inc. Israel Jun 1994
US5366875 Genetics Institute, Inc. Wozney et al. Nov 1994
US5443483 Axel Kirsch Kirsch Aug 1995
US5492697 Board of Regents, Univ. of Texas System Boyan et al. Feb 1996
US5514180 Heggeness et al. May 1996
US5520923 Genetics Institute, Inc. Tija et al. May 1996

Foreign Patent Documents

Document NumberAssigneesInventorsIssue/Pub Date
WO20WO9118098Nov 1991
WO20WO9300432Jan 1993
WO20WO9426892Nov 1994
WO20WO9426893Nov 1994

Other Publications

Is it Necessary to Decorticate Segmentally Instrumented Spines to Achieve Fusion? Ishikawa, Shin, Bowen, Cummings, SPINE, vol. 19, No. 15, pp. 1686-1690.
Experimental Spinal Fusion With Recombinant Human Bone Morphogenetic Protein-2, Schimandle, Boden, Hutton, SPINE, vol. 20, No. 12, pp. 1326-1337.
Allen, B.L. Jr.; Ferguson, R.L., In Luque Er, ed., Segmental Spinal Instrumentation, New Jersey, Charles B. Slack, Inc., 1984, pp. 185-200.
Iliac Crest Versus Spinous Process Grafts in Postraumatic Spinal Fusions, SPINE, vol. 17, No. 7, pp. 790-794, 1992.
Goldthwaite, Noel; White, Arthur H., Lumbar Spine Surgery, C.V. Mosby Company, 1987, pp. 512-523.

Referenced By

Document NumberAssigneeInventorsIssue/Pub Date
US5935133 Spinal Concepts, Inc. Erik J. Wagner et al. Aug 1999
US6030389 Spinal Concepts, Inc. Erik J. Wagner et al. Feb 2000
US5964769 Spinal Concepts, Inc. Erik J. Wagner et al. Oct 1999
US5928243 Spinal Concepts, Inc. Richard D. Guyer Jul 1999
US5904717 THM Biomedical, Inc. John H. Brekke et al. May 1999
US6080193 Spinal Concepts, Inc. Stephen H. Hochshuler et al. Jun 2000
US5981825 THM Biomedical, Inc. John H. Brekke Nov 1999
US6045579 Spinal Concepts, Inc. Stephen H. Hochshuler et al. Apr 2000
US6264701 Kensey Nash Corporation John H. Brekke Jul 2001
US5989250 Spinal Concepts, Inc. Erik J. Wagner et al. Nov 1999
US6132430 Spinal Concepts, Inc. Erik J. Wagner Oct 2000
US6053921 Spinal Concepts, Inc. Erik J. Wagner et al. Apr 2000
US5935594 THM Biomedical, Inc. Timothy Ringeisen et al. Aug 1999
US7094258 Intrinsic Therapeutics, Inc. Gregory H. Lambrecht et al. Aug 2006
US7500978 Intrinsic Therapeutics, Inc. Bogomir Gorensek et al. Mar 2009
US7611536 Warsaw Orthopedic, Inc. Gary K. Michelson Nov 2009
US6482235 Intrinsic Orthopedics, Inc. Gregory H. Lambrecht et al. Nov 2002
US7563281 Warsaw Orthopedic, Inc. William Sears et al. Jul 2009
US6562040 Spinal Concepts, Inc. Erik J. Wagner May 2003
US7252686 Boston Scientific Scimed Harold F. Carrison et al. Aug 2007
US6883520 Intrinsic Therapeutics, Inc. Gregory H. Lambrecht et al. Apr 2005
US7507243 Gregory Lambrecht et al. Mar 2009
US7540882 Warsaw Orthopedic, Inc. Gary K. Michelson Jun 2009
US7637952 Zimmer Spine, Inc. Michael E. Landry et al. Dec 2009
US6416515 Spinal Concepts, Inc. Erik J. Wagner Jul 2002
US6682533 Spinal Concepts, Inc. Michael C. Dinsdale et al. Jan 2004
US6613050 Spinal Concepts, Inc. Erik J. Wagner et al. Sep 2003
US6454769 Spinal Concepts, Inc. Erik J. Wagner et al. Sep 2002
US7455692 Warsaw Orthopedic, Inc. Gary K. Michelson Nov 2008
US6576016 Spinal Concepts, Inc. Stephen H. Hochshuler et al. Jun 2003
US7338526 Active Implants Corporation Amiram Steinberg Mar 2008
US7435262 Warsaw Orthopedic, Inc. Gary K Michelson Oct 2008
US7553329 Intrinsic Therapeutics, Inc. Gregory H. Lambrecht et al. Jun 2009
US7520888 Warsaw Orthopedic, Inc. Hai H. Trieu Apr 2009
US7553330 Intrinsic Therapeutics, Inc. Gregory H. Lambrecht et al. Jun 2009
US7615076 Anulex Technologies, Inc. Joseph C. Cauthen, III et al. Nov 2009
US7497868 Active Implants Corporation Amiram Steinberg Mar 2009
US6391030 Spinal Concepts, Inc. Erik J. Wagner et al. May 2002
US6964664 Spinal Concepts Inc. Jim Freid et al. Nov 2005
US7220281 Intrinsic Therapeutics, Inc. Gregory H. Lambrecht et al. May 2007
US7513911 Intrinsic Therapeutics, Inc. Gregory H. Lambrecht et al. Apr 2009
US6595998 SpineWave, Inc. Wes Johnson et al. Jul 2003
US7124761 Intrinsic Therapeutics, Inc. Gregory H. Lambrecht et al. Oct 2006
US7273497 Anova Corp. Bret A. Ferree Sep 2007
US7189235 Anulex Technologies, Inc. Joseph C. Cauthen Mar 2007
US7563282 Intrinsic Therapeutics, Inc. Greg H. Lambrecht et al. Jul 2009
US7862618 Warsaw Orthopedic, Inc. John White et al. Jan 2011
US7867278 Intrinsic Therapeutics, Inc. Greg H. Lambrecht et al. Jan 2011
US7879097 Intrinsic Therapeutics, Inc. Gregory H. Lambrecht et al. Feb 2011
US7909879 Anulex Technologies, Inc. Joseph C. Cauthen Mar 2011
US7905923 Anulex Technologies, Inc. Peter T. Keith et al. Mar 2011
US7658765 Intrinsic Therapeutics, Inc. Gregory H. Lambrecht et al. Feb 2010
US7670379 Anulex Technologies, Inc. Joseph C. Cauthen Mar 2010
US7717961 Intrinsic Therapeutics, Inc. Gregory H. Lambrecht et al. May 2010
US7727241 Intrinsic Therapeutics, Inc. Bogomir Gorensek et al. Jun 2010
US7749273 Anulex Technologies, Inc. Joseph C. Cauthen, III et al. Jul 2010
US7749275 Intrinsic Therapeutics, Inc. Gregory H. Lambrecht et al. Jul 2010
US7753941 Anulex Technologies, Inc. Peter T. Keith et al. Jul 2010
US7766947 Ortho Development Corporation David T. Hawkes et al. Aug 2010
US7799081 Aeolin, LLC Laurence M. McKinley Sep 2010
US7828850 Anulex Technologies, Inc. Joseph C. Cauthen, III et al. Nov 2010
US6595992 Spinal Concepts, Inc. Erik J. Wagner et al. Jul 2003
US7491219 Active Implants Corporation Amiram Steinberg Feb 2009
US7524333 Intrinsic Therapeutics, Inc. Greg H. Lambrecht et al. Apr 2009
US7534254 Warsaw Orthopedic, Inc. Gary Karlin Michelson May 2009
US7922768 Anulex Technologies, Inc. Joseph C. Cauthen, III et al. Apr 2011
US7935149 Warsaw Orthopedic, Inc. Gary K. Michelson May 2011
US7935147 Anulex Technologies, Inc. Lawrence W. Wales May 2011
US7951201 Anulex Technologies, Inc. Joseph C. Cauthen et al. May 2011
US7959679 Intrinsic Therapeutics, Inc. Greg H. Lambrecht et al. Jun 2011
US7963992 Anulex Technologies, Inc. Joseph C. Cauthen, III et al. Jun 2011
US7972337 Intrinsic Therapeutics, Inc. Thomas Boyajian et al. Jul 2011
US7985257 Anulex Technologies, Inc. Joseph C. Cauthen, III et al. Jul 2011
US8012213 Warsaw Orthopedic, Inc. William Sears et al. Sep 2011
US8002836 Intrinsic Therapeutics, Inc. Gregory H. Lambrecht Aug 2011
US7998213 Intrinsic Therapeutics, Inc. Greg H. Lambrecht et al. Aug 2011
US7993405 Anulex Technologies, Inc. Joseph C. Cauthen, III et al. Aug 2011
US8029541 Simpirica Spine, Inc. Todd Alamin et al. Oct 2011
US8025677 Zimmer Spine, Inc. Jim Freid et al. Sep 2011
US8025698 Intrinsic Therapeutics, Inc. Gregory H. Lambrecht Sep 2011
US8021425 Intrinsic Therapeutics, Inc. Gregory H. Lambrecht Sep 2011
US8048160 Anulex Technologies, Inc. Joseph C. Cauthen Nov 2011
US8034112 Anulex Technologies, Inc. Joseph C. Cauthen, III et al. Oct 2011
US8088165 Anulex Technologies, Inc. Joseph C. Cauthen, III et al. Jan 2012
US8075623 Spine Wave, Inc. Wesley D. Johnson et al. Dec 2011
US8105363 The Board of Trustees of the Leland Stanford Junior University Louis Fielding et al. Jan 2012
US8114082 Intrinsic Therapeutics, Inc. Thomas Boyajian et al. Feb 2012
US8128698 Anulex Technologies, Inc. Ishmael Bentley et al. Mar 2012
US8123755 Spine Wave, Inc. Wesley D. Johnson et al. Feb 2012
US8231678 Intrinsic Therapeutics, Inc. Gregory Lambrecht Jul 2012
US8216275 The Board of Trustees of the Leland Stanford Junior University Louis Fielding et al. Jul 2012
US8162982 Simpirica Spine, Inc. Todd Alamin et al. Apr 2012
US8163018 Warsaw Orthopedic, Inc. Hai H. Trieu Apr 2012
US8163022 Anulex Technologies, Inc. Ishmael Bentley et al. Apr 2012
US8206398 Spine Wave, Inc. Wesley D. Johnson et al. Jun 2012
US8187305 Simpirica Spine, Inc. Hugues Malandain et al. May 2012
US8187307 Simpirica Spine, Inc. Todd Alamin et al. May 2012
US8257437 Intrinsic Therapeutics, Inc. Greg H. Lambrecht et al. Sep 2012
US8292957 Warsaw Orthopedic, Inc. Gary K. Michelson Oct 2012
US8308771 Simpirica Spine, Inc. Ian Bennett et al. Nov 2012

Patent Family