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US6323321: Antibody 97A6

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Filing Information

Inventor(s) Hans-Jörg Bühring ·
Assignee(s) Eberhard-Karls-Universitat Tubingen Universitatsklinikum ·
Attorney/Agent(s) Oppenheimer Wolff & Donnelly LLP · Claude A. S. Hamrick ·
Primary Examiner Christopher L. Chin ·
Assistant Examiner Lisa V. Cook ·
Application Number US9344271
Filing date 06/30/1999
Issue date 11/27/2001
Predicted expiration date 02/26/2018
U.S. Classifications 530/387.2  · 435/287  · 424/130.1  · 424/178.1  · 424/184.1  · 424/941  · 424/851  · 424/277.1  · 435/4  · 435/5  · 435/7  · 435/6  · 435/71  · 435/721  · 435/14  · 435/701  · 435/46  · 424/152.1  · 435/325  · 435/289  · 436/500  · 436/806  · 436/95  · 436/169  · 436/120  · 436/808  · 436/805  · 436/170  · 436/119  · 436/817  · 436/291  · 436/153.12  · 530/387.1  · 424/931  ·
International Classifications --
Kind CodeB1
International Classifications 424 931 · 4241521 · 4241301 · 4241781 · 4241841 · 424 941 · 424 851 · 4242771 · 435 4 · 435 5 · 435 7 · 435 6 · 435500 · 435 71 · 435 721 · 435 14 · 435 701 · 435 46 · 435287 · 435289 · 435325 · 436291 · 436817 · 43615312 · 436119 · 436120 · 436808 · 436169 · 436170 · 436805 · 436 95 · 436806 · 436500 · 5303871 · 5303872 ·
Related U.S. Application DataCROSS REFERENCE TO RELATED APPLICATIONS
This application is a continuation-in-part of application Ser. No. 09/031,386 filed on Feb. 26, 1998, now abandoned, which is a conterpart U.S. application to German application No. 197,088,77.5 filed in Federal Republic of Germany on Mar. 5, 1997.
Foreign Priority DE19708877 - 03/05/1997 ·
8 Claims, 2 Drawings


Abstract

The present invention relates to a monoclonal antibody binding an antigen on the megakaryocytic cell line UT-7. The invention further relates to hybridoma cells producing such an antibody.

Independent Claims | See all claims (8)

  1. 1. A monoclonal antibody which binds to an antigen on the megakaryocytic cell line UT-7, produced and released by hybridoma cells deposited on Feb. 12, 1997 at the International Depository DSMZ, German Collection of Microorganisms and Cell Cultures Ltd., Mascheroder Weg 1b, D-38124 Braunschweig, Germany, under No. DSM ACC2297, in accordance with the Budapest Agreement, the antibody having the designation 97A6 or P50.
  2. 2. Hybridoma cells deposited on Feb. 12, 1997 at the International Depository DSMZ, German Collection of Microorganisms and Cell Cultures Ltd., Mascheroder Weg 1b, D-38124 Braunschweig, Germany, under No. DSM ACC2297, in accordance with the Budapest Agreement.

References Cited

Foreign Patent Documents

Document NumberAssigneesInventorsIssue/Pub Date
JP06141852A*May 1999
* cited by examiner

Other Publications

Harlow et al., “Labeling Antibodies”, in, Antibodies: A Laboratory Manual. Chapter 9, pp. 319-3358, Jan. 1988.*
Komatsu et al., Establishment and Characterization of a humna Leukemic cell line., Cancer Research, 51, 341-348, Jan. 1, 1991.*
Yoshida et al., Studies on natral ST2 gene products in the humna leukemic cell line UT-7 using monoclonal antihuman st2 antibodies., Hybridoma, vol. 14, No. 5, 1995.*
Wu et al., Indentification of IgG Fc receptor type II on humna megakaryoblastic cell lines., British Journal of Haematology, 1993, 84 pp.204-211.*
Takafuta et al., Expression of platelet membrane glycoprotein V in humna magakaryocytes and megakayocytic cell lines., Thromb. Haemostasis., 1994, 72(5), 762-769.*
Van den Oudenrijn et al., “Reactivity of the blind monoclonal antibody panel of the platelet section with megakaryocytic cell lines and cultured CD34 cells” Tissue Antigens-6th International workshop and conference on human leukocyte differentiation anti, Nov. 1996.*
Van Den Oudenrijn S. et al., “Reactivity of the Blind Monoclonal Antibody Panel of the Platelet Section With Megakaryocytic Cell Lines and Cultured CD34Cells”
Winderbank K. et al., Acute Megakaryocytic Leukemia (M7) in Childred,

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