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US6451578: Non-A, non-B, non-C, non-D, non-E hepatitis reagents and methods for their use

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Filing Information

Inventor(s) John N. Simons · Tami J. Pilot-Matias · George J. Dawson · George G. Schlauder · Suresh M. Desai · Thomas P. Leary · Anthony Scott Muerhoff · James Carl Erker · Sheri L. Buijk · Isa K. Mushahwar ·
Assignee(s) Abbott Laboratories ·
Attorney/Agent(s) Cheryl L. Becker · Dianne Casuto ·
Primary Examiner Donna Wortman ·
Application Number US8469260
Filing date 06/06/1995
Issue date 09/17/2002
Predicted expiration date 02/14/2014
U.S. Classifications 435/235.1  · 435/5  · 436/820  ·
International Classifications --
Kind CodeB1
International Classifications 4241841 · 4242041 · 4242251 · 4352351 · 435325 · 435 5 · 514 1 · 530350 · 436820 ·
Related U.S. Application DataThis application is a divisional of U.S. Ser. No. 08/424,550 filed Jun. 5, 1995 which is a continuation-in-part application of U.S. Ser. No. 08/377,557 filed Jan. 30, 1995, abandoned which is a continuation-in-part of U.S. Ser. No. 08/344,185 filed Nov. 23, 1994, abandoned, and U.S. Ser. No. 08/344,190 filed Nov. 23, 1994, abandoned, which are each continuation-in-part applications of Ser. No. 08/283,314 filed Jul. 29, 1994, abandoned, which is a continuation-in-part application of U.S. Ser. No. 08/242,654, filed May 13, 1994, abandoned, which is a continuation-in-part application of U.S. Ser. No. 08/196,030 filed Feb. 14, 1994, abandoned, all of which enjoy common ownership and each of which is incorporated herein by reference.
2 Claims, 49 Drawings


Abstract

Hepatitis GB Virus (HGBV) nucleic acid and amino acid sequences useful for a variety of diagnostic and therapeutic applications, kits for using the HGBV nucleic acid or amino acid sequences, HGBV immunogenic particles, and antibodies which specifically bind to HGBV. Also provided are methods for producing antibodies, polyclonal or monoclonal, from the HGBV nucleic acid or amino acid sequences.

Independent Claims | See all claims (2)

  1. 1. Partially purified hepatitis GB virus (HGBV), comprising an HGVB antigen, wherein said HGBV antigen (a) comprises a sequence of at least 8 contiguous amino acids, (b) is encoded by a positive stranded RNA viral genome wherein said viral genome encodes a polyprotein represented by SEQUENCE I.D. NO 387 and (c) exhibits no immunoreactivity with an antibody that specifically binds to hepatitis C virus.
  2. 2. Partially purified hepatitis GB virus (HGBV) comprising an HGBV antigen, wherein said HGBV antigen has a contiguous sequence of at least 15 amino acids, and said HGBV antigen exhibits an amino acid sequence represented by SEQUENCE I.D. NO. 387.

References Cited

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Referenced By

Document NumberAssigneeInventorsIssue/Pub Date
US7662927 ZymoGenetics, LLC Paul O. Sheppard et al. Feb 2010
US7951531 University of Iowa Research Foundation Jack T. Stapleton et al. May 2011

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