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US6660509: Methods and devices for remediation and fermentation

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Filing Information

Inventor(s) Heath H. Herman · Tod M. Herman · Arlan K. Andrews, Sr. ·
Assignee(s) Kinetic Biosystems, Inc. ·
Attorney/Agent(s) Kilpatrick Stockton LLP ·
Primary Examiner David A. Redding ·
Application Number US9316566
Filing date 05/21/1999
Issue date 12/09/2003
Predicted expiration date 03/28/2015
U.S. Classifications 435/174  · 435/394  · 435/681  · 435/403  · 435/176  ·
International Classifications --
Kind CodeB1
International Classifications 435 41 · 435 681 · 435 701 · 435 711 · 435171 · 435348 · 435366 · 435394 · 435410 · 4352865 · 4352867 · 4352891 · 435813 · 435174 · 435176 · 935 85 · 935 87 · 935 88 ·
Related U.S. Application DataCROSS-REFERENCE TO RELATED APPLICATIONS
This application claims priority to U.S. Provisional Patent Application Nos. 60/086,209, filed May 21, 1998 and 60/086,918, filed May 27, 1998, and this application is a continuation-in-part of U.S. patent application Ser. No. 09/224,645, filed Dec. 31, 1998, now U.S. Pat. No. 6,388,998 which is a continuation-in-part of U.S. patent application Ser. No. 09/115,109, filed Jul. 13, 1998, now U.S. Pat. No. 6,133,019 which is a continuation-in-part of U.S. patent application Ser. No. 08/784,718, filed Jan. 16, 1997, now U.S. Pat. No. 5,821,116, which is a division Ser. No. 08/412,289, of U.S. Pat. No. 5,622,819, filed Mar. 28, 1995.
6 Claims, 57 Drawings


Abstract

Abstract of the Invention The present invention comprises novel culture methods and devices in which living cells or subcellular biocatalysts are immobilized by the opposition of forces. The immobilized cells or biocatalysts may be attached to support complexes that add to the resultant vector forces. One embodiment of the apparatus comprises a cruciform design. Commercial applications of the apparatus include efficient isolation of metals from ores and removal of gases.

Independent Claims | See all claims (6)

  1. 1. A method of immobilizing a biocatalyst comprising: containing a biocatalyst in a chamber affected by a gravitational force; rotating a chamber about a substantially horizontal rotational axis to create a centrifugal force field; pumping a liquid medium to the chamber, wherein liquid medium creates a continuous flow of liquid, but the liquid medium does not include a gaseous phase; wherein the continuous flow of liquid creates a force; and regulating a hydraulic pressure of the chamber at a pressure greater than ambient barometric pressure, so that a resultant vector summation of all forces including the centrifugal force field, the liquid flow force and the gravitational force, acts on the biocatalyst such that the effect of the gravitational force on the biocatalyst is negated and reduced to a periodic vibration, and the biocatalyst being substantially immobilized at a position in the chamber by the resultant vector summation of all forces.

References Cited

U.S. Patent Documents

Document NumberAssigneesInventorsIssue/Pub Date
US2616619 MACLEOD NORMAN A MacLeod Nov 1952
US3450598 FLOW LAB Welsh et al. Jun 1969
US3580840 LITTON SYSTEMS INC Uridil May 1971
US3717551 BIZZINI B Bizzini et al. Feb 1973
US3753731 CHRIST C Christ Aug 1973
US3821087 DEDRICK R Knazek et al. Jun 1974
US3843454 ABBOTT LAB Weiss Oct 1974
US3865695 AGRICOLE DE MYCELIUM DU CENTRE Massier Feb 1975
US3871961 GIANESSI MATILDE Gianessi Mar 1975
US3883393 US HEALTH EDUCATION & WELFARE Knazek et al. May 1975
US3928142 Smith Dec 1975
US3941662 Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V. Munder et al. Mar 1976
US3948732 Instrumentation Laboratory, Inc. Haddad et al. Apr 1976
US3968035 Eli Lilly and Company Howe Jul 1976
US3997396 Monsanto Company Delente Dec 1976
US4001090 Societe d'Assistance Technique pour Produits Nestle S.A. Kalina Jan 1977
US4036693 Massachusetts Institute of Technology Levine et al. Jul 1977
US4059485 Monsanto Company Tolbert et al. Nov 1977
US4087327 Monsanto Company Feder et al. May 1978
US4113173 Baxter Travenol Laboratories, Inc. Lolachi Sep 1978
US4114802 Baxter Travenol Laboratories, Inc. Brown Sep 1978
US4148689 Sanraku-Ocean Co., Ltd. Hino et al. Apr 1979
US4166768 Monsanto Company Tolbert et al. Sep 1979
US4169010 Phillips Petroleum Company Marwil Sep 1979
US4178209 Monsanto Company Tolbert et al. Dec 1979
US4184916 Monsanto Company Tolbert et al. Jan 1980
US4184922 The Government of the United States Knazek et al. Jan 1980
US4189534 Massachusetts Institute of Technology Levine et al. Feb 1980
US4195131 PAPAS GARY R Papas Mar 1980
US4201845 Monsanto Company Feder et al. May 1980
US4203801 Burroughs Wellcome Co. Telling et al. May 1980
US4220725 United States of America Knazek et al. Sep 1980
US4225671 Battelle-Institut e.V. Puchinger et al. Sep 1980
US4237033 Merck & Co., Inc. Scattergood Dec 1980
US4237218 Bio-Rad Laboratories, Inc. Monthony et al. Dec 1980
US4266032 Monsanto Company Miller et al. May 1981
US4279753 Arco Environmental Company Nielson et al. Jul 1981
US4289854 Monsanto Company Tolbert et al. Sep 1981
US4293654 Massachusetts Institute of Technology Levine et al. Oct 1981
US4296882 Terumo Corporation Kobayashi Oct 1981
US4308351 LEIGHTON JOSEPH Leighton et al. Dec 1981
US4335215 Monsanto Company Tolbert et al. Jun 1982
US4372484 Gambro AB Larsson et al. Feb 1983
US4391912 Asahi Kasei Kogyo Kabushiki Kaisha Yoshida et al. Jul 1983
US4413058 ARCURI EDWARD J Arcuri et al. Nov 1983
US4425112 The United States of America as represented by the Department of Health and Human Services Ito Jan 1984
US4442206 Stanford University Michaels et al. Apr 1984
US4463019 Kikkoman Corporation Okuhara et al. Jul 1984
US4537860 Monsanto Company Tolbert et al. Aug 1985
US4546085 A/S Nunc Johannson et al. Oct 1985
US4557504 KUHNS ROGER J Kuhns Dec 1985
US4603109 Norton Company Lillo Jul 1986
US4661455 Dorr-Oliver Incorporated Hubbard Apr 1987
US4683062 Ceskoslovenska akademie ved Krovák et al. Jul 1987
US4693983 National Research Development Corporation Davies et al. Sep 1987
US4722902 Endotronics, Inc. Harm et al. Feb 1988
US4734372 Brown University Research Foundation Rotman Mar 1988
US4748124 E. I. Du Pont de Nemours and Company Vogler May 1988
US4764471 Nabisco Brands, Inc. Ripka Aug 1988
US4774187 S Diessel Gmbh & Co. Lehmann Sep 1988
US4804628 Endotronics, Inc. Cracauer et al. Feb 1989
US4833083 Sepragen Corporation Saxena May 1989
US4833089 Shimadzu Corporation Kojima et al. May 1989
US4837390 Keyes Offshore, Inc. Reneau Jun 1989
US4839292 CREMONESE JOSEPH G Cremonese Jun 1989
US4851354 Trustees of the University of Pennsylvania Winston et al. Jul 1989
US4874358 Utah Bioreseach, Inc. Brimhall et al. Oct 1989
US4894342 C. D. Medical, Inc. Guinn et al. Jan 1990
US4895806 Millipore Ireland B.V. Le et al. Jan 1990
US4897359 Bio-Response, Inc. Oakley et al. Jan 1990
US4898718 Cipan-Companhia Industrial Produtora De Antibioticos, S. A. Cardoso Feb 1990
US4908319 SMYCZEK PETER J Smyczek et al. Mar 1990
US4931401 La Societe de Recherche Snc Inc. Safi Jun 1990
US4937196 Brunswick Corporation Wrasidlo et al. Jun 1990
US4939087 Washington State University Research Foundation, Inc. Van Wie et al. Jul 1990
US5151368 Technical Research Associates, Inc. Brimhall et al. Sep 1992
US5248613 ROUBICEK RUDOLF V Roubicek Sep 1993
US5272075 Large Scale Biology Corporation Anderson et al. Dec 1993
US5437998 Synthecon, Inc. Schwarz et al. Aug 1995
US5622819 Kinetic Biosystems, Inc. Herman Apr 1997
US5665594 Synthecon, Inc. Schwarz et al. Sep 1997
US5686301 Heraeus Instruments GmbH Falkenberg et al. Nov 1997
US5702941 Synthecon, Inc. Schwarz Dec 1997
US5763279 Synthecon, Inc. Schwarz et al. Jun 1998
US5821116 Kinetic Biosystems, Inc. Herman Oct 1998
US5989913 Charles Daniel Anderson Anderson et al. Nov 1999
US5998202 Synthecon, Inc. Schwarz et al. Dec 1999
US6133019* Kinetic Biosystems, Inc. Herman Oct 2000
US6214617* Kinetic Biosystems, Inc. Herman Apr 2001

Foreign Patent Documents

Document NumberAssigneesInventorsIssue/Pub Date
D370263Falkenberg et al.May 1996
EP0431464SNOW BRAND MILK PRODUCTS CO., LTD.Jun 1991
EP0431464SNOW BRAND MILK PRODUCTS CO., LTD.Feb 1994
JP54114474Nov 1979
JP62100279SANKI ENG KKMay 1987
WO200105956BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC.Jan 2001
* cited by examiner

Other Publications

Lindahl, P.E., “Principle of a Counter-streaming Centrifuge for the Separation of Particles of Different Sizes”,
Morton, H., “A Survey of Commercially Available Tissue Culture Media”,
Sanderson et al., “Cell Separations by Counterflow Centrifugation”,
Clark et al., “Optimizing Culture Conditions for the Production of Animal Cells in Microcarrier Culture”,
, vol. 8, No. 22, p. 16 (Nov. 14, 1994).

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