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US6669687: Apparatus and methods for treating tissue

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Filing Information

Inventor(s) Vahid Saadat ·
Assignee(s) None listed in document.
Attorney/Agent(s) Morrison & Foerster LLP ·
Primary Examiner Linda C. M. Dvorak ·
Assistant Examiner Ahmed M. Farah ·
Application Number US9602436
Filing date 06/23/2000
Issue date 12/30/2003
Predicted expiration date 04/11/2021
Patent term adjustment 292
U.S. Classifications 606/14  · 607/116  · 606/41  · 606/49  · 606/15  · 607/122  · 604/22  · 604/916  · 606/7  ·
International Classifications --
Kind CodeB1
International Classifications 606 13- 16 · 606 27- 29 · 606 49- 51 · 604 20- 22 · 607119-122 · 607129-131 · 623 21- 24 · 606 41 · 606 45 · 606159 · 604 30 · 604916 · 607115 · 607116 ·
Related U.S. Application DataREFERENCE TO RELATED APPLICATIONS
The present application claims benefit from the filing date of provisional U.S. patent application Ser. No. 60/141,077 filed Jun. 25, 1999.
48 Claims, 16 Drawings


Abstract

Apparatus and methods are provided for thermally or mechanically treating tissue, such as valvular structures, to reconfigure or shrink the tissue in a controlled manner, thereby improving or restoring tissue function. The apparatus comprises a catheter in communication with an end effector. The end effector induces a temperature rise in an annulus of tissue surrounding the leaflets of a valve sufficient to cause shrinkage of the tissue, thereby reducing a diameter of the annulus and causing the valves to close more tightly. Alternatively, the end effector selectively induces a temperature rise in the chordae tendineae sufficient to cause a controlled degree of shortening of the chordae tendineae, thereby enabling the valve leaflets to be properly aligned. In another alternative, the end effector is configured to mechanically shorten the effective length of the chordae tendineae by forcing the tendineae through a tortuous path, again properly aligning the valve leaflets.

Independent Claims | See all claims (48)

  1. 1. Apparatus for treating tissue at a target site to modify flow through a valve, the apparatus comprising: a catheter having a distal end region, the catheter configured for transluminal delivery of the end region to the target site; and an end effector in communication with the distal end region, the end effector configured to approximate the shape of the tissue while transferring energy to the tissue at the target site to induce thermal shrinkage of collagen in the tissue, thereby modifying flow through the valve by reducing a circumference of the valve.
  2. 33. A method for altering flow through a valve, the method comprising: providing apparatus comprising a catheter having a distal end region, and an end effector in communication with the end region; transluminally positioning the end effector in communication with tissue at a treatment site in the vicinity of the valve such that the end effector approximates a shape of the tissue; and transferring energy from the end effector to the tissue at the treatment site to shrink collagen in the tissue, thereby altering flow through the valve by reducing a circumference of the valve.

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Patent Family

Document NumberAssigneeInventorsIssue/Pub Date
AU5884400 SAADAT VAHID SAADAT VAHID Jan 2001
US6669687 Vahid Saadat Dec 2003
EP1198213 Vahid Saadat Vahid Saadat Jun 2010