Immunogenic formulations comprising oil bodies
Filing Information
- Patent Number: US6761914
- Application Number: US9880901
- Filing date: 06/15/2001
- Issue date: 07/13/2004
- Prior Publication Data:
- US20020071846 - 06/13/2002
- Predicted expiration date: 05/27/2018
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analyzing 100 million+ documents to uncover your network...- U.S. Classifications: 424/776 · 424/758 · 424/400 · 424/725 · 424/731 · 424/757 · 424/283.1 · 424/768 · 424/776 · 424/812 · 514/885 · 424/278.1 ·
- International Classifications: --
- International Classifications: 424400 · 4242781 · 4242831 · 424812 · 424725 · 424731 · 424757 · 424758 · 424768 · 424776 · 514885 ·
- Related U.S. Application Data:
This application is a continuation-in-part of U.S. patent application Ser. No. 09/577,147 filed May 24, 2000 now U.S. Pat. No. 6,372,234 which is a continuation-in-part of U.S. patent application Ser. No. 09/448,600 filed Nov. 24, 1999, now U.S. Pat. No. 6,183,762, which is a continuation-in-part of U.S. patent application Ser. No. 09/084,777 filed May 27, 1998, now U. Pat. No. 6,146,645, which claims benefit from U.S. provisional application No. 60/075,863, filed on Feb. 25, 1998 (now abandoned); U.S. provisional application No. 60/075,864 filed on Feb. 25, 1998 (now abandoned); U.S. provisional application No. 60/047,779, filed on May 28, 1997 (now abandoned); U.S. provisional application No. 60/047,753, filed May 27, 1997 (now abandoned). This application also claims benefit from U.S. provisional application No. 60/212,130, filed Jun. 16, 2000. All of the prior applications are incorporated herein by reference in their entirety. - View document at: (opens new window):
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Abstract
The present invention provides novel adjuvants which comprise oil bodies. The invention also provides vaccine formulations comprising oil bodies and an antigen and methods for preparing the vaccines and the use of the vaccines to elicit an immune response.References Cited
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Referenced By
| Document Number | Assignee | Inventors | Issue/Pub Date |
|---|---|---|---|
| US7585645 | Sembiosys Genetics Inc. | Harm M. Deckers et al. | Sep 2009 |
| US7601858 | GS Cleantech Corporation | David Fred Cantrell et al. | Oct 2009 |
| US7608729 | GS Cleantech Corporation | David J. Winsness et al. | Oct 2009 |
Patent Family
| Document Number | Assignee | Inventors | Issue/Pub Date |
|---|---|---|---|
| US20020071846 | Gijs Rooijen et al. | Jun 2002 | |
| US6761914 | SemBioSys Genetics Inc. | Harm M. Deckers et al. | Jul 2004 |
Independent Claims | See all claims (13)
- 1. An immunogenic formulation comprising (a) an emulsion comprising substantially intact, washed oil bodies obtained from plant seeds, and (b) an antigen.
- 6. A method for preparing an immunogenic emulsion formulation comprising: (1) obtaining substantially intact oil bodies form a plant cell; (2) washing the oil bodies to obtain a washed oil body preparation; (3) formulating the washed oil body preparation into an emulsion; and (4) adding an antigen.
- 10. A method of eliciting an immune response comprising administering an effective amount of an immunogenic formulation comprising (a) an emulsion comprising substantially intact, washed oil bodies obtained from plant seeds, and (b) an antigen to an animal in need thereof.
