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US7682373: Vascular wound closure device and method

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Filing Information

Inventor(s) Yong Hua Zhu · Wolff M. Kirsch ·
Assignee(s) Loma Linda University Medical Center ·
Attorney/Agent(s) Knobbe, Martens, Olson & Bear, LLP ·
Primary Examiner Anhtuan T Nguyen ·
Assistant Examiner Kathleen Sonnett ·
Application Number US10463754
Filing date 06/16/2003
Issue date 03/23/2010
Prior Publication Data
Predicted expiration date 07/03/2023
Patent term adjustment 701
U.S. Classifications 606/213  · 604/59  · 604/15  ·
International Classifications A61B1703  ·
Kind CodeB2
Related U.S. Application DataRELATED APPLICATIONS
This application claims priority to U.S. Application Ser. No. 60/389,239, which was filed Jun. 14, 2002, the entirety of which is hereby incorporated by reference. This application also claims priority as a continuation-in-part of U.S. application Ser. No. 09/921,158, now U.S. Pat. No. 6,890,342, which was filed on Aug. 1, 2001, and which claims priority to U.S. Application Ser. No. 60/222,525, filed on Aug. 2, 2000, the entirety of both of which is hereby incorporated by reference.
35 Claims, 32 Drawings


Abstract

A method and apparatus for closing a vascular wound includes a guidewire and/or other surgical implement extending from the wound. A hemostatic material is advanced over the surgical implement and into contact with an area of the blood vessel surrounding the wound. The surgical implement is removed. Blood soaks the hemostatic material, and blood clotting is facilitated by the hemostatic agent within the material. A sealing layer of adhesive can be applied to the hemostatic material, confining the blood flow to the material. Thus, the vascular puncture wound is sealed by natural blood clot formation.

Independent Claims | See all claims (35)

  1. 1. An assembly for closing a vascular wound comprising: a hemostatic material adapted to facilitate blood clotting sufficient to close the vascular wound; a delivery tube defining a chamber configured to accommodate the hemostatic material therewithin, the delivery tube having a proximal end and a distal end, the hemostatic material being carried within the chamber; an apparatus configured to position the distal end of the delivery tube at or near a vascular wound; and a pusher member having a distal portion configured to fit at least partially through the proximal end of the delivery tube without deforming the delivery tube, the pusher member and delivery tube releasably connected to one another with the distal portion of the pusher member fit at least partially into the proximal end of the delivery tube and proximal of the hemostatic material within the chamber, a portion of the pusher member having a diameter larger than an inner diameter of at least a portion of the delivery tube; wherein the pusher member and delivery tube are configured so that as the pusher member is moved distally relative to the delivery tube while the hemostatic material remains within the chamber, the pusher member engages the delivery tube proximal of at least a portion of the hemostatic material and through that engagement deforms the delivery tube so as to create at least one opening for the hemostatic material to exit the chamber.
  2. 21. A method for closing a vascular wound, comprising: providing an assembly comprising a delivery tube and a pusher member, the delivery tube defining a chamber having a hemostatic material disposed therewithin, the pusher member having a distal portion configured to fit at least partially through a proximal end of the delivery tube, an engagement portion of the pusher member having a diameter larger than an inner diameter of at least a portion of the delivery tube, the chamber being substantially closed so that the hemostatic material remains enclosed within the chamber and the pusher member engagement portion disposed generally proximal of the hemostatic material; positioning the distal end of the delivery tube at or near a vascular wound; and moving the pusher member distally relative to the delivery tube so that the engagement portion of the pusher member engages the delivery tube at a location proximal to at least a portion of the hemostatic material and deforms at least a portion of the delivery tube so as to create at least one opening; wherein after the at least one opening is formed by the pusher member deforming the delivery tube, the hemostatic material begins to be dispatched from the chamber, and the hemostatic material is dispatched from the chamber through the at least one opening.
  3. 30. An assembly for closing a vascular wound comprising: a hemostatic material; a delivery tube having a proximal end and a distal end, an inner wall of the delivery tube defining a chamber that accommodates the hemostatic material therewithin, a first portion of the chamber having a first diameter, a second portion of the chamber being proximal of the first portion and having a second diameter greater than the first diameter, and a third portion of the chamber being proximal of the second portion and having a third diameter greater than the second diameter; a catheter extending through the delivery tube, the chamber being defined between the catheter and the inner wall, the distal end of the delivery tube engaging the catheter so that the chamber is closed at its distal end; an apparatus configured to position the distal end of the delivery tube at or near a vascular wound; a pusher member having an engagement portion configured to fit within the third portion of the chamber, the engagement portion of the pusher member having a diameter greater than the first and second chamber portion diameters, but less than or equal to the third chamber portion diameter; and the hemostatic material being within the chamber between the first portion and the third portion, the chamber enclosing the hemostatic material therewithin, the engagement portion of the pusher member being disposed generally proximal of the hemostatic material; wherein the pusher member and chamber are configured so that when the pusher member is moved distally relative to the delivery tube, the hemostatic material remains enclosed within the chamber and generally distal of the pusher member engagement portion until the pusher member engagement portion engages the inner wall in the second chamber portion and deforms the delivery tube so that at least one opening is created in the chamber, and the pusher member dispatches the hemostatic material through the at least one opening created when the pusher member deforms the delivery tube.

References Cited

U.S. Patent Documents

Document NumberAssigneesInventorsIssue/Pub Date
US1064307 Fleming Jun 1913
US3518993 AMERICAN HOSPITAL SUPPLY CORP Blake Jul 1970
US3653388 BATTELLE DEVELOPMENT CORP Tenckhoff Apr 1972
US3893454 STILLE WERNER AB Hagelin Jul 1975
US4116469* Harriman et al. Sep 1978
US4166469* LITTLEFORD PHILIP O Littleford Sep 1979
US4317445 Baxter Travenol Laboratories, Inc. Robinson Mar 1982
US4412832* Baxter Travenol Laboratories, Inc. Kling et al. Nov 1983
US4451256* Intermedicat GmbH Weikl et al. May 1984
US4530698 The United States of America as represented by the Department of Health and Human Services Goldstein et al. Jul 1985
US4532134* MALETTE WILLIAM GRAHAM Malette et al. Jul 1985
US4585437 SIMMS MARK D Simms Apr 1986
US4622970 The Johns Hopkins University Wozniak Nov 1986
US4738658 Aries Medical Incorporated Magro et al. Apr 1988
US4772266 Catheter Technology Corp. Groshong Sep 1988
US4821719 FOGARTY THOMAS J Fogarty Apr 1989
US4865593 Sherwood Medical Company Ogawa et al. Sep 1989
US4889112 Waltap Ltd. Schachner et al. Dec 1989
US4890612 Kensey Nash Corporation Kensey Jan 1990
US4900303 LEMELSON JEROME H Lemelson Feb 1990
US4921479 GRAYZEL JOSEPH Grayzel May 1990
US4961729 VAILLANCOURT VINCENT L Vaillancourt Oct 1990
US4984564 YUEN FRANK Yuen Jan 1991
US5002557 HASSON HARRITH M Hasson Mar 1991
US5057083 C. R. Bard, Inc. Gellman Oct 1991
US5152279 WILK PETER J Wilk Oct 1992
US5176128 ANDRESE CRAIG A Andrese Jan 1993
US5176129 Tekdyne, Inc. Smith Jan 1993
US5183464 Interventional Thermodynamics, Inc. Dubrul et al. Feb 1993
US5192301* Nippon Zeon Co., Ltd. Kamiya et al. Mar 1993
US5222974 Kensey Nash Corporation Kensey et al. Jun 1993
US5242387 Brigham & Women's Hospital Loughlin Sep 1993
US5250033 Interventional Thermodynamics, Inc. Evans et al. Oct 1993
US5257979 Jagpal Nov 1993
US5259835 Tri-Point Medical L.P. Clark et al. Nov 1993
US5282827 Kensey Nash Corporation Kensey et al. Feb 1994
US5290310* Howmedica, Inc. Makower et al. Mar 1994
US5292332 LEE BENJAMIN I Lee Mar 1994
US5300065 Proclosure Inc. Anderson Apr 1994
US5306254 Kensey Nash Corporation Nash et al. Apr 1994
US5320639 Meadox Medicals, Inc. Rudnick Jun 1994
US5324306 Howmedica, Inc. Makower et al. Jun 1994
US5391183 Datascope Investment Corp Janzen et al. Feb 1995
US5423814 Loma Linda University Medical Center Zhu et al. Jun 1995
US5431639 Boston Scientific Corporation Shaw Jul 1995
US5437631* Datascope Investment Corp. Janzen Aug 1995
US5443484* Loma Linda University Medical Center Kirsch et al. Aug 1995
US5626601 Gary Gershony Gershony et al. May 1997
US5643318 Boston Scientific Corporation Tsukernik et al. Jul 1997
US5665106 Hemodynamics, Inc. Hammerslag Sep 1997
US5665107 Hemodynamics, Inc. Hammerslag Sep 1997
US5674231 United States Surgical Corporation Green et al. Oct 1997
US5676689* Kensey Nash Corporation Kensey et al. Oct 1997
US5725551 Myers et al. Mar 1998
US5728132 Tricardia, L.L.C. Van Tassel et al. Mar 1998
US5759194 Hemodynamics, Inc. Hammerslag Jun 1998
US5810810 Scimed Life Systems, Inc. Tay et al. Sep 1998
US5836970 The Kendall Company Pandit Nov 1998
US5843124* Hemodynamics, Inc. Hammerslag Dec 1998
US5876387 Biovac Medizintechnik GmbH Killian et al. Mar 1999
US5910155* United States Surgical Corporation Ratcliff et al. Jun 1999
US5928266 X-Site, L.L.C. Kontos Jul 1999
US5944730 Cardio Medical Solutions, Inc. Nobles et al. Aug 1999
US5971956 BioSurgical Corporation Epstein Oct 1999
US6004341* Loma Linda University Medical Center Zhu et al. Dec 1999
US6007563 Kensey Nash Corporation Nash et al. Dec 1999
US6033413 Endocare, Inc. Mikus et al. Mar 2000
US6048358 Barak Apr 2000
US6056768 Cates et al. May 2000
US6060461 Drake May 2000
US6155265 Hemodynamics, Inc. Hammerslag Dec 2000
US5589269 Minnesota Mining and Manufacturing Company Zhu et al. Feb 2001
US6197042 Medical Technology Group, Inc. Ginn et al. Mar 2001
US6198016 3M Innovative Properties Company Lucast et al. Mar 2001
US6277140 Integrated Vascular Systems, Inc. Ginn et al. Aug 2001
US6287322 Loma Linda University Medical Center Zhu et al. Sep 2001
US6287323 Hemodynamics, Inc. Hammerslag Sep 2001
US6315753 Sub-Q, Inc. Cragg et al. Nov 2001
US6325789 Datascope Investment Corporation Janzen et al. Dec 2001
US6346093 SciMed Life Systems, Inc. Allman et al. Feb 2002
US6371974 Sub Q, Inc. Brenneman et al. Apr 2002
US6391048 Integrated Vascular Systems, Inc. Ginn et al. May 2002
US6425901* Loma Linda University Medical Center Zhu et al. Jul 2002
US6461364 Integrated Vascular Systems, Inc. Ginn et al. Oct 2002
US6508828 Radi Medical Systems AB Akerfeldt et al. Jan 2003
US6524326 Loma Linda University Medical Center Zhu et al. Feb 2003
US6623510 Integrated Vascular Systems, Inc. Carley et al. Sep 2003
US6626918 Medical Technology Group Ginn et al. Sep 2003
US6632238 Integrated Vascular Systems, Inc. Ginn et al. Oct 2003
US6649162 Baxter Aktiengesellschaft Biering et al. Nov 2003
US6890342 Loma Linda University Zhu et al. May 2005
US6964675* Loma Linda University Medical Center Zhu et al. Nov 2005
US7201725 Sub-Q, Inc. Cragg et al. Apr 2007
US20010004710 Felt et al. Jun 2001
US20010018598 Cruise et al. Aug 2001
US20020002386 Integrated Vascular Systems, Inc. Ginn et al. Jan 2002
US20020022822 Cragg et al. Feb 2002
US20020072768 Ginn Jun 2002
US20020077656 Integrated Vascular Systems, Inc. Ginn et al. Jun 2002
US20020077657 Integrated Vascular Systems, Inc. Ginn et al. Jun 2002
US20020147479 Integrated Vascular Systems, Inc. Aldrich Oct 2002
US20030023267 Core Medical, Inc. Ginn Jan 2003
US20030044380 Zhu et al. Mar 2003
US20030045893 Integrated Vascular Systems, Inc. Ginn Mar 2003
US20030050590 Kirsch Mar 2003
US20030050665 Integrated Vascular Systems, Inc. Ginn Mar 2003
US20030078598 Integrated Vascular Systems, Inc. Ginn et al. Apr 2003
US20030109820 Gross et al. Jun 2003
US20030158577 Integrated Vascular Systems, Inc. Ginn et al. Aug 2003
US20030158578 Integrated Vascular Systems, Inc. Pantages et al. Aug 2003
US20030167050 Prosl et al. Sep 2003
US20050095275 Zhu et al. May 2005
US20050107826* Zhu et al. May 2005
US20050118238 Zhu et al. Jun 2005
US20050123588 Zhu et al. Jun 2005
US20050142172 Kirsch et al. Jun 2005
US20050209637* ZHU YONG H Zhu et al. Sep 2005
US20050240137 ZHU YONG H Zhu et al. Oct 2005
US20060064124* Zhu et al. Mar 2006
US20070123816 ZHU YONG H Zhu et al. May 2007

Foreign Patent Documents

Document NumberAssigneesInventorsIssue/Pub Date
CA2274066UNIV LOMA LINDA MEDFeb 2006
CA2334226UNIV LOMA LINDA MEDApr 2006
DE9202738Sep 1992
EP0482350DATASCOPE INVESTMENT CORP.Apr 1992
EP0493810NOVOSTE CORPORATION a Florida Corporation)Jul 1992
EP0646350CORDIS EUROPA N.V.Apr 1995
EP0493810NOVOSTE CORPORATION a Florida Corporation)Nov 1995
EP0745350Hiroshi SasakiDec 1996
EP0818178X-Site, L.L.C.Mar 1997
EP0788769Cordis CorporationAug 1997
EP0955900LOMA LINDA UNIVERSITY MEDICAL CENTERJul 2005
GB2142244STREATFIELD GILL STEVENJan 1985
GB2318295GLEESON MALACHYApr 1998
WO199325148Dec 1993
WO199421306Sep 1994
WO199505206Feb 1995
WO199624291Aug 1996
WO199720505Jun 1997
WO199824374Jun 1998
WO199962405LOMA LINDA UNIVERSITY MEDICAL CENTERDec 1999
WO200002488Shlomo BARAKJan 2000
WO200007640ANGIOLINK CORPORATIONFeb 2000
WO200019912Geoffrey H. WHITEApr 2000
WO200033744UNIVERSITY OF VIRGINIA PATENT FOUNDATIONMay 2000
WO200162159LOMA LINDA UNIVERSITY MEDICAL CENTERFeb 2001
WO200134238JANIN GROUP, INC.May 2001
WO200205865SUB-Q, INC.Jan 2002
WO200209591LOMA LINDA UNIVERSITY MEDICAL CENTERFeb 2002
WO2003008002LOMA LINDA UNIVERSITY MEDICAL CENTERJan 2003
WO2003008003LOMA LINDA UNIVERSITY MEDICAL CENTERJan 2003
WO2004110284SCIMED LIFE SYSTEMS, INC.Dec 2004
WO2007044510LOMA LINDA UNIVERSITY MEDICAL CENTERApr 2007
* cited by examiner

Other Publications

“Medafor, Inc., Adds Two Management Team Members”, Press Release, Jun. 7, 2001 http://www.medafor.com/news0601.html.*
Angio-Seal, Hemostasis Puncture Closure Device Brochure, Sherwood Medical Co., Jun. 11, 1997.
Gershony, Gary, M.D., A Novel Femoral Access Site Closure Device: Duet, Early European Clinical Trials, Los Angeles Cardiology Associates, Seminar, Coronary Interventions, Oct. 16-18, 1997.
“Microporous Polysaccharide Hemispheres Provides Effective Topical Hemostasis in a Human Modified Bleeding Time Incision Model” by Medafore, Sep. 2002.
* cited by examiner

Referenced By

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Patent Family

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